Risk of Diabetes in Young Turner Syndrome Patients
Completed
Conditions studied: Turner Syndrome
In brief
Turner Syndrome is a common genetic disorder. Seventy percent of adults with Turner Syndrome have abnormalities in glucose metabolism which can lead to diabetes. The current screening guidelines for diabetes in Turner Syndrome are not specific and involve a fasting blood sugar once a year. The objective of this study is to determine if there are abnormalities in glucose metabolism and pancreatic function in young girls with Turner Syndrome. The study hypothesis is that pancreatic dysfunction (specifically of the beta cells that make insulin) is more prevalent in girls with Turner Syndrome compared to healthy controls.
Key facts
- Study ID
- NCT02160717
- Run by
- Children's Hospital Medical Center, Cincinnati
- People needed
- 120
- Starts
- 2014-05-01
- Expected to finish
- 2017-06-01
- Last updated by the study team
- 2017-08-23
Who can join
Age: 6 and older, up to 22. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Turner Syndrome confirmed by chromosomal testing
- On standard therapy (growth hormone and or estrogen)
You may not qualify if…
- Type 1 or Type 2 diabetes
- Polycystic Ovarian Syndrome
- Pregnancy
- On any medications that alter blood sugar
- Healthy Female Controls:
- Inclusion Criteria:
- Healthy
- Exclusion Criteria:
- Type 1 or Type 2 diabetes
- Polycystic Ovarian Syndrome
- Pregnancy
- On any medications that alter blood sugar
Where it is running
- Children's Hospital Medical Center, Cincinnati — Cincinnati, Ohio, United States
Full record on ClinicalTrials.gov
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