Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries

Completed · Not applicable

Conditions studied: Whiplash Associated Disorders, WAD, Whiplash

In brief

This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC). The objective is to demonstrate that the presence of muscle and spinal cord degeneration and associated muscle weakness is the consequence of a mild MVC-related injury involving the cervical spinal cord.

Key facts

Study ID

NCT02157038

Run by

Northwestern University

People needed

97

Starts

2014-07-01

Expected to finish

2020-05-01

Last updated by the study team

2021-01-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and Females (18 - 65 years of age)
• Individuals less than one week post MVA with a primary complaint of neck pain.
• Able to give written informed consent and complete interviews in English

You may not qualify if…

• Individuals with a spinal fracture from the MVA, or spinal surgeries
• History of one or more MVAs or previous diagnosis of cervical or lumbar radiculopathy
• History of neurological disorders (e.g. Multiple Sclerosis, previous stroke, myelopathy), inflammatory diseases (e.g. Hepatitis, Systemic Lupus Erythematosus, Rheumatoid Arthritis or Osteoarthritis, Alzheimers, Ankylosing Spondylitis, Crohn's disease, Fibromyalgia) or metabolic disorders (e.g. Diabetes, hyper- and hypo-thyroidism)
• Standard contraindications to MRI: claustrophobia, metallic implants, pacemaker and pregnancy.

Where it is running

• Northwestern University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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