Neuromuscular Electrical Stimulation and Mobility in Multiple Sclerosis

Completed · Not applicable

Conditions studied: Multiple Sclerosis

In brief

The purpose of this study is to investigate the capacity of a 6-week treatment with neuromuscular electrical stimulation to improve walking in individuals whose mobility has been compromised by multiple sclerosis.

Key facts

Study ID

NCT02152085

Run by

University of Colorado, Boulder

People needed

29

Starts

2014-05-01

Expected to finish

2017-12-31

Last updated by the study team

2021-05-07

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Able to read, understand, and speak English to ensure safe participation in the project
• Difficulties with walking
• On stable doses of Ampyra, provigil, or other symptomatic-treating medications
• No systemic steroids within the last 30 days
• Not currently exercising more than 2x/wk
• Able to arrange own transportation to and from the laboratories
• Provide informed consent, including willingness to be randomly assigned to one of the two groups

You may not qualify if…

• Documented MS-related relapse in the last 3 months
• Medical diagnosis or condition that is considered to be an absolute or relative contraindication to participating in exercise training, such as major renal, pulmonary, hepatic, cardiac, gastrointestinal, HIV, cancer (other than treated basal cell cancer), other neurological disorders, or pregnancy
• Poorly controlled diabetes mellitus or hypertension
• History of seizure disorders
• Alcohol dependence or abuse (≥2 drinks/day), or present history (last 6 months) of drug abuse
• Inability to attend exercise sessions 3 days per week for 6 weeks

Where it is running

• University of Colorado — Boulder, Colorado, United States

Full record on ClinicalTrials.gov

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