Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects

Completed · Not applicable · Has a placebo group

Conditions studied: Gut Microbiota, Adiposity

In brief

The purpose of this study is to investigate the effects of a synbiotic (ProSynbiotic) on the gut microbiota composition, body composition and adiposity-related genes and metabolic markers in healthy overweight adult subjects.

Key facts

Study ID

NCT02151825

Run by

Texas State University, San Marcos

People needed

54

Starts

2011-09-01

Expected to finish

2012-10-01

Last updated by the study team

2014-05-30

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age between 18-64
• BMI of 25-34.9 and/or a waist circumference >35 inches for women and >40 inches for men
• Generally healthy except for overweight or moderately obese
• A signed consent form
• Passed a screening questionnaire and willingness to comply with study procedures
• Lipid levels, fasting glucose, liver function and complete blood counts within the normal reference ranges as measured in a screening blood sample

You may not qualify if…

• Persons on a weight-loss regimen
• Antibiotic use (< 3 months before the study)
• Regular probiotic, prebiotic or synbiotic use (< 1 month before the study)
• Regular use of anti-inflammatory drugs, weight-loss medications or supplements (< 1 month prior to the study)
• Personal history of cardiovascular disease, hypertension, cancer, type 1 or type 2 diabetes and inflammatory gastrointestinal disorders such as Crohn's disease or colitis
• Smoking
• Consumption of >2 units of alcohol per day
• Pregnancy or lactation
• Irregular periods, menopause or hormone replacement therapy
• Over 300 minutes of exercise per week

Where it is running

• Texas State University — San Marcos, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.