Circulating Tumor Cells in Operative Blood

Completed

Conditions studied: Carcinoma, Pancreatic Ductal

In brief

It is hypothesized that circulating tumor cells (CTCs) from pancreatic adenocarcinoma are released into the peritoneal cavity through blood lost during the surgical resection of these tumors resulting in peritoneal recurrence despite appropriate surgical resection. Targeting the mechanisms responsible for CTC adhesion to the peritoneum may result in inhibition of implantation and growth, thus preventing this mode of pancreatic cancer recurrence postoperatively.

Key facts

Study ID

NCT02150746

Run by

University of Florida

People needed

3

Starts

2015-02-01

Expected to finish

2016-02-01

Last updated by the study team

2016-02-23

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed tissue diagnosis of pancreatic ductal adenocarcinoma
• Scheduled to undergo pancreatectomy (open or minimally invasive) with curative intent
• Aged 18-85 years
• No race restrictions

You may not qualify if…

• Patients who have undergone preoperative therapy with either chemotherapy, radiation therapy, or both
• Serum CA19-9 less than 200ng/ml
• Patients with prior history of gastrointestinal malignancy

Where it is running

• Shands Hospital at the University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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