Immune Responses to the Flu Shot During Pregnancy

Completed

Conditions studied: Pregnancy

In brief

This study will examine effects of everyday life stress and obesity on immune responses to influenza virus vaccine (the flu shot) during pregnancy. Following vaccination, antibody levels against influenza (the flu) increase. Higher antibody levels indicate better immune protection from influenza. In addition to providing protection from the flu for yourself, being vaccinated during pregnancy may protect your baby from the flu during the first six months of life during which time infants cannot be vaccinated. Our primary goals are to determine whether greater life stress and obesity reduce 1) antibody responses to the flu shot in women and 2) antibody levels in the newborn at the time of delivery.

Key facts

Study ID

NCT02148874

Run by

Lisa Christian

People needed

287

Starts

2013-10-01

Expected to finish

2019-08-01

Last updated by the study team

2019-09-24

Who can join

Age: 18 and older, up to 42. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• less than 29 weeks pregnant
• ages 18-42
• planning to deliver at The Ohio State University Wexner Medical Center

You may not qualify if…

• prior serious adverse reaction to seasonal influenza vaccine

Where it is running

• The Ohio State University Wexner Medical Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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