A Public Health Program to Reduce Risk of Antepartum Depression
Completed · Not applicable
Conditions studied: Depression
In brief
The hypotheses were as follows: H1. Women at low-moderate risk for APD at T1 (baseline EPDS scores of 5-9) in the cognitive behavioral intervention (CBI) group will maintain low-moderate risk status and have significantly fewer APD symptoms at T2 and T3 than women at low-moderate risk for APD in the (TAU) control group (as measured by percent of participants with EPDS scores \<9 at T2 and T3 and mean score changes). H2: Women at high risk for APD at T1 (baseline EPDS scores ≥10) in the CBI group will have a significantly greater reduction in APD symptoms at T2 and T3 than women at high risk for APD in the TAU control group (as measured by percent of participants with EPDS scores \<10 at T2 and T3 and mean score changes).
Key facts
- Study ID
- NCT02144844
- Run by
- East Carolina University
- People needed
- 146
- Starts
- 2010-12-01
- Expected to finish
- 2013-11-01
- Last updated by the study team
- 2014-05-22
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- 18 years of age or older
- Between 6-30 weeks pregnant
- Enrolled as a patient at the local health department (LHD) or Brody School of Medicine Regional Perinatal Center (BSOM-RPC)
- Self-identified as African American, Caucasian, or Hispanic
- Able to read at a 4th grade level;
- Have a or score >4 on the Edinburgh Postnatal Depression Scale (EPDS)
- Are willing to complete the informed consent form
- Enrolled in Medicaid or are low-income based on Women's Infant and Children (WIC) eligibility criteria.
You may not qualify if…
- Have had a spontaneous abortion before 20 weeks of pregnancy
- Diagnosed with schizophrenia or bipolar disorder with or without psychosis, or are currently receiving treatment for depression; or have an organic mental disorder
- Diagnosed with a high-risk pregnancy that requires bed rest or hospitalization-- Demonstrated an active suicidal plan
- Had a concurrent medical condition, such as hypothyroidism, that would explain depression.
Where it is running
- Brody School of Medicine Regional Perinatal Center — Greenville, North Carolina, United States
- Pitt County Health Department — Greenville, North Carolina, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.