Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

Completed · Not applicable · Has a placebo group

Conditions studied: Disorder of Urinary Stent, Ureteral Spasm, Ureteropelvic Junction Obstruction, Urolithiasis

In brief

This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent. The investigators plan to learn how often this occurs and whether it can be prevented. The investigators hypothesize that children who have a temporary, indwelling ureteral stent will experience a significantly less post-operative pain if given a non-steroidal anti-inflammatory (NSAID) prior to removal of the ureteral stent when compared to placebo. The investigators hypothesize that the incidence of severe post-stent removal pain is similar to an adult population.

Key facts

Study ID: NCT02140970
Run by: University of Colorado, Denver
People needed: 51
Starts: 2014-05-01
Expected to finish: 2020-01-11
Last updated by the study team: 2021-04-26

Who can join

Age: 4 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

ages 4-17
unilateral ureteral stent placed after ureteropelvic junction obstruction repair or treatment of upper tract urolithiasis

You may not qualify if…

bilateral stents
undergoing other concomitant procedure at time of planned ureteral stent removal
indication for stent other than ureteropelvic junction obstruction repair or treatment of upper tract urolithiasis
pregnant
developmental delay
allergy to ibuprofen or non-steroidal anti-inflammatory medication class
chronic kidney disease
prior renal transplant
history of nasal polyps
history of asthma

Where it is running

Children's Hospital Colorado — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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