Evaluation of an Herbal-Based De-Pigmenting System

Completed · Phase 4

Conditions studied: Melasma, Hyperpigmentation

In brief

The purpose of this study is to evaluate the effectiveness and tolerability of an herbal de-pigmenting regimen applied to one side of the face compared with hydroquinone applied to the other side of the face in treating mottled hyperpigmentation and melasma.

Key facts

Study ID

NCT02138539

Run by

Sadick Research Group

People needed

28

Starts

2013-10-01

Expected to finish

2014-10-01

Last updated by the study team

2015-11-18

Who can join

Age: 30 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female age 30-65
• Must be in good general health
• Must be willing to use sunscreen on the face daily
• Must be willing to avoid tanning beds and excessive exposure to direct sunlight
• Must be willing to continue using regular cosmetic regimen

You may not qualify if…

• Nursing pregnant/ planning to become pregnant during the course of the study
• Using a medication that increases sensitivity to sunlight including doxycycline, minocycline, tetracycline, ciprofloxin, hydrochlorothiazide, and sulfonamides.
• Any known allergies/sensitivities to facial skincare products, anti-aging products, de-pigmenting products, or products containing hydroquinone
• Usage of any new skincare products during the course of the study
• Presence of atopic dermatitis or psoriasis on the face
• Uncontrolled diabetes, hypertension, hypothyroidism, hyperthyroidism
• TCA or other deep peels within 1 year or medium to light peels within 3 months prior to starting the study
• Facial/laser treatment within the last 3 months
• Facial cosmetic surgery within the last 12 months
• Use of product, topical, or systemic medication, known to affect dyschromia, having "whitening" or anti-aging properties
• Physical skin conditions such as excessive hair, scarring, tattoos that might impair evaluations of the test sites
• Active hepatitis, immune deficiency, or autoimmune disease

Where it is running

• Sadick Research Group — New York, New York, United States

Full record on ClinicalTrials.gov

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