Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD
Completed · Not applicable
Conditions studied: Coronary Artery Disease, Inflammation
In brief
In this randomized study the investigators aim to determine the effects of a whole-food plant-based vegan diet on markers of inflammation and glucometabolic profile in patients with cardiovascular disease. The investigators hypothesize that a whole-food plant-based vegan diet will reduce markers of inflammation and improve glucometabolic profile compared with the American Heart Association (AHA)- recommended diet at 2 months follow-up in patients with coronary artery disease (CAD). The investigators are also evaluating endothelial function using the EndoPAT device and stool microbiome.
Key facts
- Study ID
- NCT02135939
- Run by
- NYU Langone Health
- People needed
- 100
- Starts
- 2014-03-11
- Expected to finish
- 2018-03-01
- Last updated by the study team
- 2018-04-24
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects on stable medical therapy for at least 7-10 days post-coronary angiography and found to have CAD (defined as >50% lesion in an artery with >2mm caliber) .
You may not qualify if…
- Failure of the Treatment Self-Regulation Questionnaire
- Use of steroids or non-steroidal anti-inflammatory medications other than aspirin
- Use of probiotics or over the counter supplements other than standard vitamins
- Have a history of myocardial infarction or active infection within the preceding 3 months
- Have a history of an eating disorder or colon cleansing or are already on a whole-food plant-based vegan diet
- Have a planned PCI during the study period
- Are participating in a competing study
- Have any condition or situation that, in the investigator's opinion, may confound the study results, or may interfere significantly with the patient's ability to adhere with study procedures
Where it is running
- NYUMC Tisch Hospital, HCC 14 — New York, New York, United States
Full record on ClinicalTrials.gov
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