Efficacy, Pharmacokinetics, and Safety of Presatovir in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection
Completed · Phase 2 · Has a placebo group
Conditions studied: Respiratory Syncytial Virus Infection
In brief
The primary objective of this study is to evaluate the effects of presatovir on respiratory syncytial virus (RSV) viral load in RSV-positive adults who have been hospitalized with acute respiratory infectious symptoms. Participants will receive 1 dose of presatovir on Day 1 and followed for 27 days postdose. Nasal swabs will be collected at each study visit (excluding Day 28) and assayed for change in viral load as the primary endpoint.
Key facts
- Study ID
- NCT02135614
- Run by
- Gilead Sciences
- People needed
- 189
- Starts
- 2014-06-09
- Expected to finish
- 2017-04-12
- Last updated by the study team
- 2018-09-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Northwestern Memorial Hospital — Chicago, Illinois, United States
- Anne Arundel Medical Center — Annapolis, Maryland, United States
- Henry Ford Health System — Detroit, Michigan, United States
- William Beaumont — Royal Oak, Michigan, United States
- New York Presbyterian Hospital — New York, New York, United States
- Rochester General Hospital — Rochester, New York, United States
- Vanderbilt Medical Group and Clinic — Nashville, Tennessee, United States
- University of Washington — Seattle, Washington, United States
- Marshfield Clinic Research Foundation — Marshfield, Wisconsin, United States
- John Hunter Hospital — New Lambton, New South Wales, Australia
- Westmead Hospital — Westmead, New South Wales, Australia
- Redcliffe Hospital — Redcliffe, Queensland, Australia
- Gold Coast Hospital — Southport, Queensland, Australia
- Monash Medical Center — Clayton, Victoria, Australia
- Frankston Hospital — Frankston, Victoria, Australia
- Universite Liebre de Bruxelles - Hopital Erasme — Anderlecht, Belgium
- Hopital Foch — Suresnes, Hauts-de-Seine, France
- CHRU Brest - Hospital Cavale Blanche — Brest, France
- Hopital d'Instructions des Armees Percy — Clamart, France
- Hopital Louis Mourier — Colombes, France
- Hopital Saint Louis - Service de Pneumologie — Paris, France
- Hopital Tenon — Paris, France
- Soroka Medical Center — Beersheba, Israel
- Edith Wolfson Medical Center — Holon, Israel
- Hadassah University Hospital Ein Kerem — Jerusalem, Israel
Full record on ClinicalTrials.gov
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