The Role of Obstructive Sleep Apnea in Children With Fatty Liver Disease

Stopped early · Not applicable

Conditions studied: Non Alcoholic Fatty Liver Disease

In brief

The purpose of this study is to examine whether CPAP therapy can reduce or eliminate hepatic fat accumulation in obese children and adolescents.

Key facts

Study ID

NCT02134522

Run by

Yale University

People needed

1

Starts

2014-06-01

Expected to finish

2017-04-01

Last updated by the study team

2018-06-08

Who can join

Age: 9 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Sleep Apnea as diagnosed by clinical sleep study (Apnea Hypopnea index greater than 1)
• Evidence of NAFLD as diagnosed by screening MRI (hepatic fat fraction ≥5.5%) Obese child/adolescent between 9-21 years old
• Compliance with using C-pap as instructed

You may not qualify if…

• Medications or know disease known to alter glucose or insulin metabolism such as oral steroids, or certain psychiatric medications, such as Xeleca, Lithium and Paxil.
• Type 2 Diabetes Mellitus
• Medications for chronic anti-inflammatory effects
• Consumption of alcohol

Where it is running

• Yale University — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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