Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Chronic Plaque Psoriasis (PsO)

Completed · Phase 3

Conditions studied: Plaque Psoriasis

In brief

This is a two part study comparing CHS-0214 to Enbrel in patients with chronic plaque PsO who have not yet received any biologic therapy for any indication (other than insulin or hormones).

Key facts

Study ID

NCT02134210

Run by

Coherus Oncology, Inc.

People needed

521

Starts

2014-06-16

Expected to finish

2016-05-12

Last updated by the study team

2019-06-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female adults
• PsO diagnosis for 6 months
• Active disease: PASI greater than or equal to 12, Physician's Static Global Assessment (PSGA) score greater than or equal to 3 (based on a scale or 0-5),
• Body Surface Area (BSA) involved with PsO greater than or equal to 10%
• Dermatology Life Quality Index (DQLI) greater than or equal to 10
• Previously received phototherapy or systemic non-biologic therapy for PsO

You may not qualify if…

• Forms of Psoriasis other than PsO
• Drug induced Psoriasis
• Positive QuantiFERON-tuberculosis (TB) Gold Test
• Presence of significant comorbid conditions
• Chemistry and hematology values outside protocol specified range
• Major systemic infections

Where it is running

• Radiant Research - Scottsdale — Scottsdale, Arizona, United States
• Anaheim Clinical Trials — Anaheim, California, United States
• Dream Team Clinical Research — Anaheim, California, United States
• Private Practice — Encino, California, United States
• Kaiser Permanente — Los Angeles, California, United States
• Skin Surgery Medical Group, Inc — San Diego, California, United States
• Clinical Science Institute — Santa Monica, California, United States
• Healthcare Partners Medical Group — Torrance, California, United States
• Horizons Clinical Research Center — Denver, Colorado, United States
• The Savin Center — New Haven, Connecticut, United States
• New England Research Associates — Trumbull, Connecticut, United States
• Florida Academic Dermatology Center (U of Miami Hospital) — Miami, Florida, United States
• Radiant Research - Pinellas Park — Pinellas Park, Florida, United States
• Atlantic Clinical Research Collaborative — West Palm Beach, Florida, United States
• Palm Beach Research Center — West Palm Beach, Florida, United States
• Radiant Research - Atlanta — Atlanta, Georgia, United States
• Private Practice - Jamie Weisman — Atlanta, Georgia, United States
• Altman Dermatology Associates — Arlington Heights, Illinois, United States
• Springfield Clinic — Springfield, Illinois, United States
• The Indiana Clinical Trials Center — Plainfield, Indiana, United States
• Kansas City Dermatology — Overland Park, Kansas, United States
• Derm Research — Louisville, Kentucky, United States
• Hamzavi Dermatology Clinical Research — Fort Gratiot, Michigan, United States
• Grekin Skin Institute — Warren, Michigan, United States
• Arizona Research Center — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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