Development of Kinetic Biomarkers of Liver Fibrosis Measuring NAFLD
Status unconfirmed
Conditions studied: Non-alcoholic Fatty Liver Disease
In brief
This is a small preliminary study conducted to explore new methods for the potential of aiding in diagnosis of liver fibrotic disease as well as predicting disease progression. There will be a total of 4 visits spread out over approximately 8 weeks. You will be asked to drink "heavy water" during most of that time. "Heavy Water" also known as deuterated water, is physically and chemically very similar to ordinary drinking water. It tastes and feels exactly like regular water. It is odorless and has no known harmful effects at the doses given here. Heavy water occurs naturally, and is a minor component of the water we all ingest daily.
Key facts
- Study ID
- NCT02124577
- Run by
- University of California, San Diego
- People needed
- 50
- Starts
- 2014-05-01
- Expected to finish
- 2021-05-01
- Last updated by the study team
- 2021-05-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (≥ 18 years of age)
- Adult male and female subjects, all races, ethnic groups, social and economic backgrounds and health status who are scheduled to undergo a liver biopsy as part of routine medical care will be included in the research.
- Willingness to follow-up for 8 weeks
- Written inform consent.
You may not qualify if…
- Children younger than 18 will be excluded, since growth of liver tissue may confound measurements of collagen synthesis and cell proliferation due to normal turnover or disease.
- The eligibility of patients will be determined by Dr. Rohit Loomba, MD or a referring physician at the time the potential subject is recommended to undergo a liver biopsy procedure as part of their medical treatment.
Where it is running
- University of California, San Diego — San Diego, California, United States (enrolling)
Full record on ClinicalTrials.gov
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