Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
Completed · Not applicable · Has a placebo group
Conditions studied: Arthroplasty, Replacement, Knee, Nerve Block
In brief
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement. Specifically we are studying adductor canal nerve blocks in conjunction with epidural anesthesia, which is a combination that has not been extensively researched before. Our question is whether combining these modalities will enhance patient satisfaction after surgery and accelerate patients' readiness to discharge.
Key facts
- Study ID
- NCT02121392
- Run by
- University of Chicago
- People needed
- 165
- Starts
- 2014-10-01
- Expected to finish
- 2017-01-01
- Last updated by the study team
- 2020-10-20
Who can join
Age: any, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- end stage degenerative joint disease
- enrolled for unilateral total knee arthroplasty at the University of Chicago
- age < 85
- ability to understand and willingness to sign a written informed consent
You may not qualify if…
- age > 85
- American Society of Anesthesiologists physical status > 3
- known hypersensitivity to lidocaine, bupivacaine, ropivacaine or other local anesthetic agents
- Coagulopathy, specifically INR > 1.5, Platelets < 100, therapy with clopidogrel within 5 days prior to surgery, enoxaparin or fondaparinux within the last 24 hours prior to surgery, patients with anti-phospholipid syndrome requiring aggressive anticoagulation perioperatively
- History of alcohol or substance abuse (including strong opioids - morphine, oxycodone, methadone, fentanyl, ketobemidone), taking > 50 mg morphine equivalent daily of opioids
- Pre-existing femoral neuropathy or radiculopathy
- Patients with poor ability to communicate
Where it is running
- University of Chicago Medicine — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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