Effects of a Structured Exercise Program on Cancer-Related Fatigue in Women Receiving Radiation Therapy for Breast Cancer
Completed · Not applicable
Conditions studied: Breast Cancer
In brief
Radiation therapy (RT) is often used to treat breast cancer. RT combined with breast surgery is associated with better outcomes in early stage breast cancer compared to surgery alone. Fatigue is one of the most important side effects of RT because it can decrease patients' quality of life. Studies found that physical activity (PA) may help to improve quality of life in cancer survivors. PA has been reported to lower fatigue, anxiety, and depression. Physical inactivity over a long period of time may lead to rapid energy and physical function loss. PA intervention studies in patients undergoing RT have included mostly White patients. There is no evidence on African American patients undergoing RT. The purpose of this study is to examine the efficacy of a structured, moderate-intensity, aerobic exercise program in reducing cancer-related fatigue in African Americans undergoing RT for localized breast cancer.
Key facts
- Study ID
- NCT02117011
- Run by
- Georgetown University
- People needed
- 27
- Starts
- 2013-06-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2020-01-27
Who can join
Age: 18 and older, up to 74. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- -over 18 years old or less than 75 years old.
- histologically confirmed carcinoma of the breast
- radiation therapy naive
- sedentary, as defined as <60 minutes of recreation or work requiring modest PA/week based on the 7 day physical activity recall questionnaire
- ambulatory
- negative serum pregnancy test and not planning to be pregnant in the next 3 months
- ability to understand and the willingness to sign a written informed consent.
- have breast cancer stage 0-IIIA
- completed neo-adjuvant or adjuvant chemotherapy may be concurrently receiving endocrine or HER2 directed therapy
You may not qualify if…
- age less than 18 years old or more than 75 years
- no histological confirmation of breast cancer
- prior breast, chest or pelvic radiotherapy
- concurrent chemotherapy
- distant metastases
- physical limitations (e.g., orthopedic, central nervous system) that contraindicate participation in a low to moderate intensity home-based walking program
- a positive pregnancy test, currently pregnant or planning to become pregnant in the next three months
- identified as the active or maintenance stage of exercise behavior
- psychiatric disorder which would render the subject unable to provide informed consent.
Where it is running
- Washington Cancer Institute at Washington Hospital Center — Washington D.C., District of Columbia, United States
Full record on ClinicalTrials.gov
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