Minocycline as Neuroprotectant After Aneurysmal Subarachnoid Hemorrhage

Withdrawn before enrolling · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Subarachnoid Aneurysm Hemorrhage

In brief

The purpose of this study is to determine the safety and efficacy of a drug minocycline in improving outcomes at 3 months after rupture of an aneurysm in the head.

Key facts

Study ID

NCT02113176

Run by

University at Buffalo

People needed

0

Starts

2010-01-01

Expected to finish

2018-12-01

Last updated by the study team

2025-07-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥ 18 yrs of age
• Ruptured aneurysm
• Initiate treatment within 72 hours of SAH
• Pre Rankin ≤ 1

You may not qualify if…

• Hunt \& Hess 5 with no improvement
• ICP > 30
• No plans to treat aneurysm
• Allergy to Tetracycline / Antibiotics
• Creatinine >2
• Platelets < 75,000
• Other brain diseases
• Previous infection requiring Tetracycline

Where it is running

• University of Buffalo Neurosurgery — Buffalo, New York, United States

Full record on ClinicalTrials.gov

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