PAIN - Postoperative Analgesia INvestigation

Completed · Phase 4

Conditions studied: Postoperative Pain

In brief

The purpose of this study is to assess the efficacy of the intraoperative injection of prolonged acting (liposomal) bupivacaine in postoperative pain control after truncal surgical incisions.

Key facts

Study ID

NCT02111746

Run by

The University of Texas Health Science Center, Houston

People needed

350

Starts

2013-11-20

Expected to finish

2017-06-30

Last updated by the study team

2018-10-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years-old or older, and
• Sternotomy, thoracotomy, laparotomy or mini-thoracotomy incision is planned
• There is reasonable expectation that the patient will be extubated within 24 hours after surgery

You may not qualify if…

• The patient has a known allergy to morphine or any opioid
• The patient has a known chronic pain disorder or takes daily opioid medication > 1 month prior to surgery
• There is anticipated difficulty communicating pain status due to language or other barriers at the investigator discretion
• High postoperative morbidity index based on preoperative assessment, such as, low likelihood of extubation within 24 hours, extensive thoracoabdominal aortic aneurysm (Extent 2 TAAA), preoperative renal insufficiency/failure, etc.

Where it is running

• Department of Cardiothoracic and Vascular Surgery and Memorial Hermann Heart and Vascular Institute - Texas Medical Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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