A Phase 1b/2a Study Evaluating AMG 232 in Metastatic Melanoma

Completed · Phase 1

Conditions studied: Advanced Malignancy, Advanced Solid Tumors, Cancer, Oncology, Oncology Patients, Tumors, Melanoma

In brief

Phase 1b/2a, open-label, sequential dose escalation and expansion study of AMG 232 in combination with trametinib and dabrafenib in subjects with metastatic melanoma followed by a direct comparison of AMG 232 combined with trametinib and dabrafenib versus trametinib combined with dabrafenib alone.

Key facts

Study ID
NCT02110355
Run by
Kartos Therapeutics, Inc.
People needed
31
Starts
2014-12-19
Expected to finish
2018-12-27
Last updated by the study team
2021-03-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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