Observational Study of Corneal Opacities in Adults

Status unconfirmed

Conditions studied: Corneal Opacities (Scar and Stromal Dystrophy)

In brief

A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT will be used to perform 3-D corneal scans. These scans will be used to assess opacity depth and measure corneal thickness (pachymetry), corneal topography (anterior and posterior), and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imaging, will be performed for comparison.

Key facts

Study ID

NCT02109471

Run by

Oregon Health and Science University

People needed

150

Starts

2011-06-01

Expected to finish

2025-12-01

Last updated by the study team

2024-02-12

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult (18 \& older) patients presenting in OHSU Casey Eye Clinic with corneal opacities (scar and stromal dystrophy)

You may not qualify if…

• Inability to give informed consent.
• Inability to maintain stable fixation for OCT imaging.
• Inability to commit to required visits to complete the study.

Where it is running

• Humberto Martinez — Portland, Oregon, United States (enrolling)

Full record on ClinicalTrials.gov

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