Tissue and Functional Assessment of Myocardial Injury in Hodgkin Lymphoma (HL) Survivors

Completed

Conditions studied: Hodgkin Lymphoma Survivor

In brief

This study will test whether cardiac MRI can improve early detection of Hodgkin lymphoma associated heart disease compared to a stress echocardiogram. By doing both stress echocardiography and cardiac MRI, we will compare the ability of the two tests to detect heart disease.

Key facts

Study ID

NCT02106611

Run by

Memorial Sloan Kettering Cancer Center

People needed

133

Starts

2014-04-01

Expected to finish

2026-02-06

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Classical or nodular lymphocyte predominant HL treated at Memorial Sloan-Kettering Cancer Center.
• Age ≥ 18 years
• Treatment for HL that included mediastinal RT at initial diagnosis or relapse.
• ≥ 5 years from last HL treatment.

You may not qualify if…

• Primary HL diagnosis prior to 1980.
• Additional mediastinal RT or subsequent cardiotoxic systemic therapy for secondary malignant neoplasm.
• Known CAD/CHF (defined as documented myocardial infarction, cardiac revascularization, angiographic obstructive CAD, or decreased LV function [EF < 55%] during prior clinical care).
• Contraindication to MRI (i.e. pacemakers, defibrillators, or aneurysm clips, or other implanted ferromagnetic objects), gadolinium (i.e. known hypersensitivity to gadolinium, advanced renal insufficiency as defined by glomerular filtration rate <30 ml/min/1.73m\^2).
• Contraindication to exercise stress testing other than the above (i.e. unstable angina or severe valvular stenosis).

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.