Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy

Stopped early · Phase 4

Conditions studied: Hemorrhoid

In brief

The purpose of this study is to compare the quality and duration of pain relief after a hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine hcl or control with saline. It is hypothesized that liposomal bupivacaine will provide more effective postoperative pain relief than both bupivacaine hcl and the control.

Key facts

Study ID

NCT02104414

Run by

St. Luke's-Roosevelt Hospital Center

People needed

11

Starts

2014-04-01

Expected to finish

2016-01-01

Last updated by the study team

2018-12-04

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• patients undergoing hemorrhoidectomy for grade 3 or 4 hemorrhoids who are English-speaking patients, 21-65 yr of age, ASA physical status I-III, BMI<30

You may not qualify if…

• contraindications to administration of local anesthesia (e.g., local anesthetic allergy), difficult airway (Mallampati>2), psychiatric or cognitive disorders, pregnancy , and history of substance abuse or chronic opioid use

Where it is running

• St.Luke's-Roosevelt Hospital Center — New York, New York, United States

Full record on ClinicalTrials.gov

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