Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain

Stopped early · Phase 2 · Has a placebo group

Conditions studied: Neuropathic Pain

In brief

The purpose of the study is to determine the effect of oxytocin given into the spinal fluid on pain and areas and intensity of hyperalgesia and allodynia in patients with chronic neuropathic pain.

Key facts

Study ID

NCT02100956

Run by

Wake Forest University Health Sciences

People needed

8

Starts

2014-06-19

Expected to finish

2022-10-10

Last updated by the study team

2023-10-03

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Weight < or equal to 240 pounds
• Neuropathic pain for > 6 months: with primary pain area below the umbilicus

You may not qualify if…

• Hypersensitivity, allergy, or significant reaction to any ingredient of the study drug or lidocaine
• Any disease, diagnosis, or condition (medical or surgical) that, in the opinion of the Principal Investigator, would place the subject at increased risk (active gynecologic disease in which increased tone would be detrimental e.g., uterine fibroids with ongoing bleeding), compromise the subject's compliance with study procedures, or compromise the quality of the data
• Pregnancy
• spinal cord stimulators, chronic intrathecal drug therapy, or oral opioid treatment for > 3 months at a current dose of > 100 milligram (mg) morphine per day or equivalent.

Where it is running

• Wake Forest School of Medicine — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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