Negative Work Exercise for the Treatment of Knee Arthritis
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Osteoarthritis, Arthritis
In brief
The purpose of this study is to develop a negative work exercise regimen as an intervention for posttraumatic osteoarthritis (PTOA). "Negative work" is the force produced by muscles as they lengthen, and regularly occurs with common activities such as lowering an object from a shelf or walking down stairs. In this study, the investigators are examining the effectiveness of negative work exercise over a 12-week period in older, male, Veterans.
Key facts
- Study ID
- NCT02098096
- Run by
- Washington D.C. Veterans Affairs Medical Center
- People needed
- 54
- Starts
- 2014-03-01
- Expected to finish
- 2019-11-01
- Last updated by the study team
- 2018-09-20
Who can join
Age: 50 and older, up to 70. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- Adult men 50 y.o. 70 years old will be recruited for this proposed study.
- Participant inclusion criteria includes having bilateral knee OA (Kellgren-Lawrence Grade 2 or 3) and sedentary (e.g., have not engaged in 3 exercise sessions per week for 3 consecutive months).
- Gait aides and orthoses will not preclude participation in this study.
You may not qualify if…
- Exclusion criteria include uncontrolled cardiovascular disease, non-ambulatory status, neurogenic weakness, knee extensor and flexor manual muscle test < 3 out of 5, lower extremity amputation, and current participation in a supervised exercise program.
- In addition, major surgical procedures within the last six months, unstable joints, endocrine or metabolic disorders that result in excessive fatigue or muscle weakness, or use of medications that may impair exercise tolerance would also preclude participation in this study.
Where it is running
- Washington DC VA Medical Center — Washington D.C., District of Columbia, United States
Full record on ClinicalTrials.gov
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