Metabolic Biomarkers in Thoracic Cancers

Recruiting now · Not applicable

Conditions studied: Lung Cancer

In brief

The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slightly modified, sugar solution (13C-glucose) and studying a small sample of the tumor once it is removed at the time of surgery.

Key facts

Study ID

NCT02095808

Run by

University of Texas Southwestern Medical Center

People needed

200

Starts

2013-03-20

Expected to finish

2027-12-31

Last updated by the study team

2026-05-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must have known or probable malignant lesions requiring surgical biopsy or excision.
• Subjects of all races and ethnic origins over 18 years of age.

You may not qualify if…

• Not a surgical candidate.
• Poorly controlled diabetes.

Where it is running

• University of Texas Southwestern Medical Center — Dallas, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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