Heated Humidified Oxygen Compared to Dry Oxygen Therapy in Children With Bronchiolitis

Completed · Not applicable

Conditions studied: Bronchiolitis, Hypoxemia

In brief

The purpose of this study is to compare heat and humidified oxygen with cold and dry oxygen in children with bronchiolitis. The hypotheses are that heating and humidifying inspired low flow supplemental oxygen will optimize mucociliary function thereby, 1) improve oxygenation, 2) decrease work of breathing, and 3) decrease length of hospital stay.

Key facts

Study ID

NCT02094664

Run by

UCSF Benioff Children's Hospital Oakland

People needed

32

Starts

2014-01-01

Expected to finish

2015-06-01

Last updated by the study team

2018-01-08

Who can join

Age: any, up to 2. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages ≤24 months of age
• Physician diagnosed bronchiolitis
• Admitted to pediatric floor
• Supplemental oxygen requirement, <4 L/min, for hypoxemia, oxygen saturation <92% in room air

You may not qualify if…

• Prematurity, born <37 weeks gestational age
• Admitted to pediatric intensive care unit for medical indication
• Requirement of heated, humidified high flow system
• Chronic lung disease (such as bronchopulmonary dysplasia, cystic fibrosis, primary ciliary dyskinesia, tracheostomy status, baseline oxygen requirement)
• Neuromuscular disorders
• Chromosomal defects
• Metabolic disorders
• Immunodeficiency
• Unrepaired cardiac abnormalities

Where it is running

• Children's Hospital and Research Center Oakland — Oakland, California, United States

Full record on ClinicalTrials.gov

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