Leptin Receptors in the Bariatric Surgical Population Within the University of Pittsburgh Medical System: A Cohort Study

Completed

Conditions studied: Obesity

In brief

Prospective cohort study evaluating the role of leptin receptors in the bariatric surgical population compared with non obese controls. Additionally serum levels of leptin, ghrelin, motilin and PYY will be compared amongst the different BMI classes and a quality of life questionnaire completed by all participants. The hypothesis is that obese individuals have lower leptin receptors in enterocytes which is partially responsible for the higher serum leptin levels without appropriate control of satiety.

Key facts

Study ID

NCT02093416

Run by

University of Pittsburgh

People needed

50

Starts

2013-10-01

Expected to finish

2014-07-01

Last updated by the study team

2016-01-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Endoscopic Intervention

You may not qualify if…

• 18 years of age or older
• No acute GI bleeding

Where it is running

• University of Pittsburgh/UPMC Presby — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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