A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration

Stopped early · Phase 2 · Has a placebo group

Conditions studied: Geographic Atrophy, Macular Degeneration

In brief

This study will assess the safety and efficacy of the brimonidine intravitreal implant in participants with geographic atrophy due to age-related macular degeneration.

Key facts

Study ID

NCT02087085

Run by

Allergan

People needed

310

Starts

2014-05-09

Expected to finish

2018-03-30

Last updated by the study team

2019-04-23

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Geographic atrophy due to age-related macular degeneration in the study eye
• Visual acuity better than or equal to 20/125 Snellen equivalent in the study eye and 20/200 Snellen equivalent in the fellow eye.

You may not qualify if…

• Cataract surgery or Laser-Assisted in situ Keratomileusis (LASIK) in the study eye in the last 3 months
• Infections in either eye in the last 3 months

Where it is running

• Retinal Consultants of Arizona, Ltd., Retinal Research Institute — Phoenix, Arizona, United States
• Associated Retina Consultants — Phoenix, Arizona, United States
• University of California, San Diego, Jacobs Retina Center, Shiley Eye Center — La Jolla, California, United States
• Northern California Retina Vitreous Associates — Mountain View, California, United States
• Retina Consultants of Southern Colorado, PC — Colorado Springs, Colorado, United States
• "National Ophthalmic Research Institute Retina Consultants of Southwest Florida" — Fort Myers, Florida, United States
• Retina Specialty Institute — Pensacola, Florida, United States
• Retina Vitreous Associates of Florida — St. Petersburg, Florida, United States
• Southern Vitreoretinal Associates, PL — Tallahassee, Florida, United States
• Center for Retina and Macular Disease — Winter Haven, Florida, United States
• Georgia Retina — Decatur, Georgia, United States
• Raj K. Maturi, MD — Indianapolis, Indiana, United States
• Retina Associates of Western New York — Rochester, New York, United States
• Charlotte Eye Ear Nose & Throat Associates, PA — Charlotte, North Carolina, United States
• Oregon Retina, LLP — Eugene, Oregon, United States
• Casey Eye Institute, Oregon Health and Science University — Portland, Oregon, United States
• Mid Atlantic Retina, Wills Eye Retina Surgeons — Philadelphia, Pennsylvania, United States
• Retina Research Institute of Texas — Abilene, Texas, United States
• Texas Retina Associates — Arlington, Texas, United States
• "Austin Retina Associates " — Austin, Texas, United States
• Retina Foundation of the Southwest — Dallas, Texas, United States
• Valley Retina Institute — McAllen, Texas, United States
• Strategic Clinical Research Group, LLC — Willow Park, Texas, United States
• Center for Eye Research Australia — Melbourne, Victoria, Australia
• Lions Eye Institute, University of Western Australia — Nedlands, Australia

Full record on ClinicalTrials.gov

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