Non-Invasive Evaluation of Transplant Kidney Using OCT
Completed · Not applicable
Conditions studied: Chronic Kidney Disease
In brief
Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can function as a type of "optical biopsy", providing non-invasive cross-sectional images of tissue architectural morphology in situ and in real-time. This proposal will demonstrate that OCT has the ability to provide novel and valuable histopathological information regarding donor kidneys that can be used to predict post-transplant renal function. These investigations will result in a major breakthrough in increasing the number of healthy kidneys available for transplantation by making the most efficient use of available donor kidneys, eliminating the possible use of bad donor kidneys, providing an accurate measure of expected post-transplant renal function, and allowing better distinction between post-transplant immunological rejection and ischemic-induced acute renal failure.
Key facts
- Study ID
- NCT02084966
- Run by
- Georgetown University
- People needed
- 169
- Starts
- 2014-04-01
- Expected to finish
- 2018-12-01
- Last updated by the study team
- 2019-03-08
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Georgetown University Medical Center — Washington D.C., District of Columbia, United States
Full record on ClinicalTrials.gov
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