A Study To Evaluate The Effect Of Food On The Behavior Of Tofacitinib Modified Release 11 Milligram Tablets In Healthy Western And Japanese Volunteers

Completed · Phase 1

Conditions studied: Healthy

In brief

This study will evaluate the drug behavior and safety of a single dose of the 11 milligram tofacitinib (CP-690,550) modified-release formulation in 24 healthy volunteers when taken after eating a high fat meal (the effect of food). This will be compared to the drug behavior and safety of a single dose of the 11 milligram tofacitinib (CP-690,550) modified-release formulation when taken after a 10 hour fast.

Key facts

Study ID

NCT02084875

Run by

Pfizer

People needed

24

Starts

2014-04-11

Expected to finish

2014-05-25

Last updated by the study team

2018-11-30

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male volunteers and/or healthy females volunteers of non-childbearing potential who are 18 to 55 years of age;
• Healthy volunteers who are of Japanese or Western descent;
• Healthy volunteers with no evidence of active or latent or inadequately treated tuberculosis.

You may not qualify if…

• Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease;
• Clinically significant infections within the past 3 months

Where it is running

• Glendale Adventist Medical Center — Glendale, California, United States

Full record on ClinicalTrials.gov

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