Brain Function and Structure in Cocaine Dependence

Completed · Phase 2 · Has a placebo group

Conditions studied: Cocaine Dependence

In brief

The purpose of this study is to examine the role of brain MRI findings in predicting treatment outcomes among individuals with cocaine dependence.

Key facts

Study ID

NCT02080832

Run by

Virginia Commonwealth University

People needed

54

Starts

2010-02-01

Expected to finish

2016-02-01

Last updated by the study team

2017-12-26

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female subjects age 18 to 50 who meet current DSM-IV criteria for cocaine dependence who are seeking treatment.

You may not qualify if…

• Current DSM-IV diagnosis of any psychoactive substance dependence other than cocaine, marijuana, nicotine, or alcohol
• Have a DSM-IV axis I psychiatric disorder or neurological disease or disorder requiring ongoing treatment and/or making study participation unsafe
• Significant current suicidal or homicidal ideation
• Medical conditions contraindicating citalopram pharmacotherapy (liver disease, seizure disorder, bleeding disorder, or prolonged QT interval on EKG)
• Taking CNS active concomitant medications
• Taking medications known to have significant drug interactions with the study medication
• Having conditions of probation or parole requiring reports of drug use to officers of the court
• Impending incarceration
• Pregnant or breast feeding for female patients
• Inability to read, write, or speak English
• Having plans to leave the immediate geographical area within 3 months
• Unwillingness or not competent to sign a written informed consent form
• Individuals who have pacemakers, metal or electromechanical implants or metallic foreign bodies
• Patients who are known to be HIV positive will not be included due to possible CNS effects of HIV.
• Alcohol withdrawal symptoms or history of significant previous alcohol withdrawal symptoms.

Where it is running

• Virginia Commonwealth University — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.