Parkinstep: Automated PD Gait and Balance Assessment for Optimizing DBS

Completed

Conditions studied: Parkinson's Disease With Deep Brain Stimulation

In brief

Changes in deep brain stimulation (DBS) settings can have a delayed effect on gait function, which makes it impractical to optimize DBS for gait parameters in the clinic. Wearable movement sensors could be used to assess gait impairment in the patient's home hours after treatment adjustments are made in the clinic. This study aims to quantitatively evaluate the effects of turning off deep brain stimulation on lower extremity and gait function over three hours. This study will provide vital information about our patient worn system's ability to detect changes in lower impairment over time, which could be used to assist with DBS tuning for the lower extremities and gait in the future.

Key facts

Study ID

NCT02080572

Run by

Great Lakes NeuroTechnologies Inc.

People needed

22

Starts

2014-02-01

Last updated by the study team

2015-02-05

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of idiopathic Parkinson's disease
• Age > 21
• Underwent DBS surgery targeting the subthalamic nucleus (STN)
• Bilateral or midline involvement when "off" DBS/medication state
• Clinical history of gait impairment or freezing of gait

You may not qualify if…

• "Parkinson's plus" syndrome, secondary, or atypical Parkinson's disease
• Underwent DBS surgery targeting the ventral intermediate (VIM)
• Unable to walk independent of a wheelchair (use of assistive devices, like a cane, is okay for this study)
• Dementia (determined by a neuropsychological assessment).

Where it is running

• University of Cincinnati — Cincinnati, Ohio, United States
• University Hospitals of Case Western — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.