Impact of Weight Loss on Physical Function

Completed · Not applicable

Conditions studied: Obesity

In brief

We are proposing a trial to directly compare a high intensity weight loss protocol to a moderate intensity weight loss protocol to determine which leads to greater improvements in physical function in severely obese older adults.

Key facts

Study ID

NCT02079051

Run by

Wake Forest University Health Sciences

People needed

28

Starts

2014-02-01

Expected to finish

2014-11-01

Last updated by the study team

2018-08-09

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least 65 years old at the time of the initial screening visit
• BMI greater than or equal to 35 kg/m2

You may not qualify if…

• Cognitive impairment (Montreal Cognitive Assessment < 20)
• Depression (Centers for Epidemiologic Studies Depression Scale score >16
• Recent weight change (+/- 10 lbs. in the last 12 months)
• History of non-skin cancer in the last 2 years
• Cardiovascular disease event or unstable angina within the past six months, severe pulmonary disease, renal failure
• Major liver dysfunction within the last 2 years
• Recently quit smoking less than 12 months prior
• Use of estrogen or testosterone replacement therapy
• Current use of medications for psychosis or manic-depressive illness
• Use of weight-loss medications in previous 3 months
• Dependence on others for food procurement or preparation
• Poorly controlled diabetes (HgA1c greater than or equal to 9%) or blood pressure (greater than or equal to 159 mm Hg systolic or 99 mm Hg diastolic)

Where it is running

• Wake Forest Baptist Health — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.