Immune Characterization of Subcutaneous Adipose Tissue

Completed

Conditions studied: Determine Immune Cell Types in Subcutaneous Adipose Tissue

In brief

The overall goal of this proposal is to characterize the immune cell profile of subcutaneous abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate potential associations between different adipose tissue immune cell types and metabolic profile.

Key facts

Study ID

NCT02076087

Run by

Washington University School of Medicine

People needed

19

Starts

2014-02-01

Expected to finish

2017-09-01

Last updated by the study team

2017-09-07

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Women of all races and ethnicity
• Age between 18 and 65 years
• Body Mass Index (BMI) ≥ 18.5 kg/m²
• Weight stable (+/- 3% during the last 2 months before enrollment)
• Women already scheduled for above mentioned procedures

You may not qualify if…

• Diabetes Mellitus
• Recent (<5 years) history of cancer (except in situ ductal breast carcinoma)
• Chemotherapy and/or radiation therapy within 4 months before enrollment
• Immune system diseases (i.e., autoimmune disorders, acquired immunodeficiency syndrome)
• Pregnant or breastfeeding
• Take any medication that might affect immune function
• Severe organ dysfunction
• BMI <18.5 kg/m² or size of each breast is >600 grams, if scheduled for bilateral breast reconstruction

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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