Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Stopped early · Phase 3
Conditions studied: Injury of Anterior Cruciate Ligament
In brief
Anterior cruciate ligament repair using hamstring autograft in children is a painful orthopedic procedure. The current practice to provide analgesia for this procedure include femoral continuous perineural infusion and femoral single shot peripheral nerve block, along with perioperative opioids and NSAIDS both IV and orally. Since the use of opioids can be associated with adverse side effects, which include, but are not limited to nausea, vomiting, constipation, pruritus and respiratory depression, comparing the amount of opioid used with either analgesia delivery method is needed.
Key facts
- Study ID
- NCT02075411
- Run by
- Children's Hospital of Philadelphia
- People needed
- 1
- Starts
- 2014-03-01
- Expected to finish
- 2015-02-01
- Last updated by the study team
- 2016-05-18
Who can join
Age: 14 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- American Society of Anesthesiology (ASA) physical status 1 or 2
- Male or female subjects ages 14 to 18 years old at time of procedure
- Patients who undergo an ACL repair using the hamstring autograft at The Children's Hospital of Philadelphia
- Parental/guardian permission (informed consent) and if appropriate, child assent
You may not qualify if…
- Parents/patients refusal to the placement of a femoral and/or sciatic nerve block
- Contraindications to femoral and/or sciatic nerve block:
- Infection
- Neurologic deficits, including motor and/or sensory deficit of the femoral and sciatic nerves.
- Patients' inability to participate in pain scoring because of developmental delay.
- Performance of an all-epiphyseal ACL repair.
- Allergy to any of the medications used in the study.
- Presence of a coagulopathy
Where it is running
- The Children's Hospital Of Philadelphia — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.