Evaluation of Injection Techniques in Celiac Plexus Neurolysis

Completed · Not applicable

Conditions studied: Pancreatic Cancer, Pain

In brief

1\. To evaluate the efficacy of EUS-CPN in subjects who experience a sympathetic response during injection when compared with subjects who do not experience sympathetic response during injection. EUS-CPN when performed in subjects who experience a sympathetic response during injection will have better pain relief when compared to subjects who do not experience a sympathetic response during injection.

Key facts

Study ID

NCT02068677

Run by

AdventHealth

People needed

51

Starts

2013-08-01

Expected to finish

2014-11-01

Last updated by the study team

2016-04-14

Who can join

Age: 19 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Abdominal pain typical for pancreatic cancer ( pain score ≥ 3/10)
• Abdominal CT consistent with diagnosis of pancreatic cancer
• Pancreatic cancer confirmed by EUS-FNA
• Inoperable pancreatic cancer as determined during EUS or prior CT

You may not qualify if…

• Age under 19 years
• Unable to safely undergo EUS for any reason
• Coagulopathy (Prothrombin time > 18 secs, platelet count < 80,000/ml)
• Previous CPN or other neurolytic block that could affect pancreatic cancer-related pain or had implanted epidural or intrathecal analgesic therapy
• Another cause for abdominal pain such as pseudocyst, ulcer or other intrabdominal disorder
• Noncompliance such that the patient would not return for subsequent follow-up
• Active alcohol or other drug use or significant psychiatric illness
• Unable to consent
• Non-English speaking

Where it is running

• Florida Hospital — Orlando, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.