Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)
Completed · Phase 2
Conditions studied: Obsessive-Compulsive Disorder
In brief
This study investigates if a single dose of IV Ketamine can rapidly improve Obsessive-Compulsive Disorder (OCD) symptoms and whether these effect can be maintained with a condensed course of a type of Cognitive Behavioral Therapy called Exposure and Response Prevention (EX/RP). You will be compensated for your time and travel. Participants must be between the ages of 18-55.
Key facts
- Study ID
- NCT02062658
- Run by
- New York State Psychiatric Institute
- People needed
- 10
- Starts
- 2013-12-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2016-12-29
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18-55
- Physically healthy and not currently pregnant
- Primary Diagnosis of OCD
- Sufficient severity of symptoms
- Currently off all psychotropic medication OR
- Currently on adequate dose of medication for treatment of OCD, but have not achieved at least partial remission
- Able to provide consent
You may not qualify if…
- Psychiatric conditions that make participation unsafe (schizophrenia [either self or first degree relative e.g. siblings, parents], history of violence, severe depression, eating disorder, substance dependence [including nicotine])
- Female patients who are either pregnant or nursing
- Planning to commence EX/RP during the period of the study or those who have completed an adequate dose of EX/RP (defined as 8 or more sessions within 2 months) within 8 weeks prior to enrollment.
- period of the study
- Allergy to ketamine
- Participants for whom being off of medication is not clinically recommended
- Medical conditions that make participation unsafe (e.g. high blood pressure, head injury)
- Currently on medications that make participation unsafe
Where it is running
- New York State Psychiatric Insitute — New York, New York, United States
Full record on ClinicalTrials.gov
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