Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
Stopped early · Phase 4 · Has a placebo group
Conditions studied: Low Back Pain
In brief
The purpose of this project is to study the effects of preoperative followed by scheduled intravenous acetaminophen on pain control for 24 hours postoperatively after minimally invasive 1 or 2 level transforaminal lumbar interbody fusion.
Key facts
- Study ID
- NCT02061774
- Run by
- Texas Tech University Health Sciences Center
- People needed
- 21
- Starts
- 2013-10-01
- Expected to finish
- 2018-01-11
- Last updated by the study team
- 2020-05-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age > 18 years old
- Being scheduled to have elective primary minimally invasive 1 or 2 level transforaminal lumbar laminectomy interbody fusion
- ASA I, II, or III
- Informed consent form signed
You may not qualify if…
- Anyone weighing less than 50kg (as this would require a dosing change).
- Hypersensitivity or contraindication to intravenous acetaminophen or opioids
- Allergy to Methocarbamol; morphine sulfate, sevoflourane, or fentanyl
- Impairment of liver function-- defined as the inability to receive intravenous acetaminophen without dose adjustment as determined by the investigator; or history of chronic liver disease defined as history of hepatitis of any kind as recorded in the patient's chart
- Mental retardation recorded as a diagnosis in the patient's chart
- History of chronic pain (defined as currently receiving treatment from a specialist for pain)
- History of pain recalcitrant to intravenous morphine
- Impaired kidney function (defined as creatinine > 1.5)
- Anyone who is not a candidate for general anesthesia or any other portion of the investigator's standard of
Where it is running
- Texas Tech University Health Science Center — Lubbock, Texas, United States
Full record on ClinicalTrials.gov
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