Does Cricoid Pressure Reduce the Risk of Aspiration?
Completed · Not applicable
Conditions studied: Microaspiration, Acute Respiratory Distress Syndrome (ARDS), Hospital Acquired Pneumonia
In brief
In modern anesthesia practice, the application of cricoid pressure during intubation is not infrequently used with the goal of preventing gastric-to-pulmonary aspiration. The evidence to support this practice is very scarce, and there have recently been many reports in the literature questioning the safety of cricoid pressure during intubation. Therefore, the goal of this study will be to randomize those at risk for microaspiration to receive cricoid pressure versus no cricoid pressure during intubation. We will specifically exclude those patients thought to be at the highest risk of aspiration (it is considered standard of care to perform cricoid pressure during intubation of this population). We will include those patients with some risk factors for aspiration (it is not considered standard of care to apply cricoid pressure during intubation of this population).
Key facts
- Study ID
- NCT02058004
- Run by
- Mayo Clinic
- People needed
- 95
- Starts
- 2014-08-01
- Expected to finish
- 2014-10-01
- Last updated by the study team
- 2016-01-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Obesity (BMI>30)
- Diabetes mellitus
- Gastroesophageal reflux disease (GERD)
- schedule cardiac, aortic vascular or non-cardiac thoracic procedure
You may not qualify if…
- emergent surgery
- risk factors for macroaspiration (non-fasting status, bowel obstruction, achalasia, hiatal hernia, esophageal stricture, esophageal diverticulum), altered level of consciousness, known pregnancy
- preoperative ARDS
- preoperative pneumonia
Where it is running
- Mayo Clinic - Saint Mary's Campus — Rochester, Minnesota, United States
- Mayo Clinic in Rochester — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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