Increasing Motivation for Antiretroviral Therapy Initiation: A Pilot Intervention

Completed · Not applicable

Conditions studied: HIV

In brief

In this 3-year study, the investigators will develop and pilot test an intervention called Personal Approaches to Treatment Choices for HIV (PATCH). PATCH is a brief intervention designed to support participants' decision-making processes and enhance intrinsic motivation to initiate ART, using motivational interviewing (MI) techniques. The intervention will be targeted at HIV-positive African-American adults in inner-city Baltimore, Maryland who are suboptimally engaged in care and who endorse conspiracy beliefs about HIV or low readiness to begin ART. The specific aims are: (1) Develop and refine a manual for a brief MI intervention to support ART decision-making and reduce the likelihood of ART refusal: (2) Evaluate the feasibility and acceptability of implementing the PATCH intervention in a small sample of individuals who are African-American, recommended for ART but who are not current taking it, and who experience multiple barriers to ART adherence; and (3) Conduct a small randomized controlled pilot to test the potential efficacy of the PATCH intervention in producing positive attitudinal changes, including a reduction in conspiracy beliefs and perceived barriers to ART and stated readiness to begin ART.

Key facts

Study ID

NCT02055417

Run by

University of Maryland, Baltimore

People needed

50

Starts

2010-12-01

Expected to finish

2016-12-01

Last updated by the study team

2019-11-04

Who can join

Age: 21 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Known to the recruitment site to be HIV-positive
• African-American or multiracial with African-American heritage.
• Able to speak and understand English.
• At least one of the following:
• Sub-optimally involved in HIV care (defined as no regular source of HIV primary care, clinically eligible for ART but not taking it, or received an offer of ART in the last year but not currently taking it.
• Non-adherent to ART (defined as being offered ART but not taking it or not appropriately adhering to it (as reflected by a score of 10 or less on screening questionnaire) at the time of enrollment.
• Conspiracy beliefs (defined as a score of 10 or more on screening questionnaire or states that would not be ready to take ART if recommended).

You may not qualify if…

• Known diagnosis of mental retardation or dementia.
• Active psychosis or suicidality evident in initial interview.

Where it is running

• University of Maryland School of Medicine — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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