Evaluation of Wound Drainage After Knee or Hip Arthroplasty

Withdrawn before enrolling · Phase 4

Conditions studied: Complications; Arthroplasty

In brief

To compare side effects and complications relating to use of warfarin or rivaroxaban, tolerance and/or toxicity of these two agents such as drop in hemoglobin post operatively, extent of bruising, quantity of wound drainage, duration of drainage, wound swelling, sub and supra-therapeutic prothrombin times, need for transfusion, and patient tolerance in two randomized groups. Return visits to the operating room, length of stay, and VTE rates will also be compared.

Key facts

Study ID

NCT02054936

Run by

University of Michigan

People needed

0

Starts

2014-03-01

Expected to finish

2016-02-01

Last updated by the study team

2015-12-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients over the age of 18 undergoing primary hip or knee replacement by Dr. Urquhart or Dr. Hallstrom.

You may not qualify if…

• Patients with a contraindication to pharmacologic VTE prophylaxis such as hemophilia, Plavix use, active bleeding or prior reaction to warfarin or rivaroxaban, nursing mothers, hepatic disease, GFR <30, use of more than 200mg of aspirin daily, and inability to continue medication or lab monitoring after hospital discharge known preoperatively.

Where it is running

• University of Michigan Health Systems — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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