High-field Brain Magnetic Resonance Spectroscopy

Running, not enrolling

Conditions studied: Healthy

In brief

Magnetic resonance spectroscopy (MRS) allows non-invasive measurement of the concentration of up to 18 metabolites in the brain ("neurochemical profile"). The objective of this proposal is to develop new methods for high-field brain MRS (3 to 7 Tesla). Our main hypothesis is that higher magnetic fields lead to improved spatial and temporal resolution and improved quantification precision. Aims 1. To obtain improved "neurochemical profiles" in the brain using single voxel proton MRS at very high field (3 Tesla to 7 Tesla). 2. To develop new methods for proton magnetic resonance spectroscopic imaging (MRSI) to obtain metabolic maps at very high field (3 Tesla to 7 Tesla). Since this project is focused on technical development, only healthy volunteers will be recruited (no patients).

Key facts

Study ID
NCT02053701
Run by
University of Minnesota
People needed
30
Starts
2010-06-01
Expected to finish
2030-11-01
Last updated by the study team
2026-03-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

You may not qualify if…

Where it is running

Full record on ClinicalTrials.gov

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