Efficacy and Safety Study of Ozanimod in Relapsing Multiple Sclerosis

Completed · Phase 3 · Has a placebo group

Conditions studied: Relapsing Multiple Sclerosis

In brief

This study is a two-part trial consisting of Part A (see NCT01628393) and Part B, presented within this record. The primary objective of Part B is to assess whether the clinical efficacy of ozanimod (RPC1063) is superior to interferon beta-1a (IFN β-1a; Avonex®) in reducing the rate of clinical relapses at the end of Month 24 in patients with relapsing multiple sclerosis (RMS).

Key facts

Study ID

NCT02047734

Run by

Celgene

People needed

1320

Starts

2013-12-03

Expected to finish

2017-04-13

Last updated by the study team

2021-02-11

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Multiple sclerosis as diagnosed by the revised 2010 McDonald criteria
• Expanded Disability Status Scale (EDSS) score between 0 and 5.0 at baseline

You may not qualify if…

• Primary progressive multiple sclerosis

Where it is running

• Xenoscience — Phoenix, Arizona, United States
• Receptos Study Site 118 — Phoenix, Arizona, United States
• Saint Josephs Hosptial and Medical Center — Phoenix, Arizona, United States
• Territory Neurology and Research Institute — Tucson, Arizona, United States
• Receptos Study Site 119 — Tucson, Arizona, United States
• Alta Bates Summit Medical Center — Berkeley, California, United States
• Receptos Study Site 110 — Berkeley, California, United States
• Receptos Study Site 122 — Long Beach, California, United States
• Receptos Study Site 112 — Sacramento, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• Multiple Sclerosis Center at UCSF — San Francisco, California, United States
• Receptos Study Site 120 — San Francisco, California, United States
• Denver Neurological Research LLC — Denver, Colorado, United States
• Receptos Study Site 127 — Denver, Colorado, United States
• Neurology Associates PA — Maitland, Florida, United States
• Receptos Study Site 114 — Maitland, Florida, United States
• Receptos Study Site 124 — Pompano Beach, Florida, United States
• Neurostudies Inc — Port Charlotte, Florida, United States
• Receptos Study Site 123 — Port Charlotte, Florida, United States
• Infinity Clinical Research LLC — Sunrise, Florida, United States
• West Georgia Sleep Disorder Center and Neurology Associates — Douglasville, Georgia, United States
• Consultants In Neurology — Northbrook, Illinois, United States
• Receptos Study Site 113 — Northbrook, Illinois, United States
• Receptos Study Site 121 — St Louis, Missouri, United States
• Receptos Study Site 115 — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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