Cognitive Retraining and Brain Stimulation for Alcohol Use
Completed · Not applicable · Has a placebo group
Conditions studied: Binge Drinking
In brief
The overarching goal of this study is to determine whether combined cognitive training and Transcranial Direct Current Stimulation (tDCS) reduces drinking in high-risk drinkers. To this end, specific study purposes are: 1) replicate previous findings that cognitive retraining reduces drinking levels, 2) test whether cognitive retraining can be enhanced with tDCS, and 3) investigate the neural changes that result from cognitive retraining and tDCS. We hypothesize that those participants who receive alcohol avoidance cognitive training will have greater reductions in drinking. In turn, those participants who receive a higher level of applied tDCS during alcohol avoidance response training will have better avoidance learning, as well as, a larger reduction in drinking behavior. Finally, those participants receiving a higher level of applied tDCS will have more neuronal response associated with alcohol avoidance during the brain imaging session.
Key facts
- Study ID
- NCT02045108
- Run by
- The Mind Research Network
- People needed
- 77
- Starts
- 2014-01-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2018-03-20
Who can join
Age: 21 and older, up to 30. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 21-30 years
- At least five binge drinking episodes (4+ drinks for men; 3+ drinks for women) for the past month
- Alcohol Use Disorder Identification Test (AUDIT) score greater than 8
- Right handed
You may not qualify if…
- History of treatment for alcohol dependence (AD) or desire for treatment
- History of alcohol withdrawal
- History of brain injury
- Currently taking psychotropic medications (e.g. antidepressants, antipsychotics)
- Female subjects who are pregnant
- Evidence of recent illicit drug use on a urine screen
- Left handed
- Prior participation in a brain stimulation study
- Implanted brain medical devices
- Electromedical devices
- Latex allergy
Where it is running
- The Mind Research Network and University of New Mexico Center on Alcoholism, Substance Abuse and Addiction — Albuquerque, New Mexico, United States
Full record on ClinicalTrials.gov
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