Imaging Lens Deposits in Exfoliation Syndrome
Stopped early
Conditions studied: Exfoliation Syndrome, Primary Open Angle Glaucoma, Cataracts
In brief
The purpose of this study is to use a special eye imaging technique, anterior segment optical coherence tomography (AS-OCT), to image the lens (the curved, transparent part of the eye that helps you to see clearly by directing images of light onto the back of your eye) and note any changes in exfoliation syndrome. Exfoliation syndrome is a common condition that has many ways of showing up in the eye, including the formation of deposits in the eye, shakiness of the lens that can complicate cataract surgery, and a higher chance of developing a type of glaucoma called exfoliation glaucoma. In this study we plan to collect images and measure exfoliation deposits on the lens with AS-OCT, which can take high resolution pictures of the eye without requiring contact with the eye. We will compare lens images of subjects with exfoliation syndrome to those of subjects with primary open angle glaucoma and cataracts. This type of imaging could be used in patients with known diagnosis of exfoliation syndrome to track disease progression and see how they respond to possible treatments. We also hope that with this imaging technology we can detect early changes in currently unaffected eyes, which could be useful for predicting which patients may develop the disease.
Key facts
- Study ID
- NCT02042703
- Run by
- Duke University
- People needed
- 4
- Starts
- 2014-02-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2015-10-21
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of exfoliation syndrome, primary open angle glaucoma (POAG), or cataracts
You may not qualify if…
- Unable to provide or sign consent
- Pseudophakia
- Other prior intraocular surgery
- Other eye diseases other than refractive error
Where it is running
- Duke University Medical Center — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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