Sequencing T-cells in Type I Diabetes Mellitus

Completed

Conditions studied: Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2

In brief

The purpose of this study is to investigate CD8 + T-cell receptor (TCR) repertoire differences between patients with type 1 diabetes mellitus and type 2 diabetes or healthy controls.

Key facts

Study ID

NCT02040337

Run by

Seton Healthcare Family

People needed

40

Starts

2014-04-01

Expected to finish

2017-12-13

Last updated by the study team

2018-04-17

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients must have a current or previous diagnosis of Type I Diabetes (Autoimmune-related T1DA as confirmed by a positive test for glutamic acid decarboxylase (GAD) auto-antibodies. When available, idiopathic T1DB patients with a lack of autoantibodies to GAD will be recruited)
• Patients must be ≥ 18 years old and ≤55 years old
• Inclusion criteria: patients T2D as controls
• Patients must have a current or previous diagnosis of T2D
• Patients must be ≥ 18 years old and ≤55 years old

You may not qualify if…

• <18 years old; > 55 years old

Where it is running

• University of Texas Physicians at Trinity — Austin, Texas, United States

Full record on ClinicalTrials.gov

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