HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial

Completed · Not applicable

Conditions studied: Hip Fractures

In brief

HIP ATTACK is an international randomized controlled trial of 3000 patients with a hip fracture that requires a surgical intervention. This trial will determine the effect of accelerated medical clearance and accelerated surgery compared to standard care on the 90-day risk of mortality and major perioperative complication (i.e., a composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding).

Key facts

Study ID

NCT02027896

Run by

McMaster University

People needed

3001

Starts

2014-03-14

Expected to finish

2022-09-30

Last updated by the study team

2024-01-22

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age ≥45 years; and
• diagnosis of hip fracture during working hours with a low-energy mechanism (i.e., falling from standing height) requiring surgery.

You may not qualify if…

• patients requiring emergent surgery or emergent interventions for another reason (e.g., subdural hematoma, abdominal pathology requiring urgent laparotomy, acute limb ischemia, other fractures or trauma requiring emergent surgery, necrotising fasciitis, coronary revascularization, pacemaker-implantation);
• open hip fracture;
• bilateral hip fractures;
• peri-prosthetic fracture;
• therapeutic anticoagulation not induced by a Vitamin K Antagonist, unfractionated heparin, (e.g., administration of therapeutic Low Molecular Weight Heparin (LMWH) (>6,000 u/24h) in the 24 hours prior to enrolment, or intake of any other non-reversible oral anticoagulant(s) for which there is no reversing agent available
• patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);
• patients refusing participation; or
• patients previously enrolled in the study.

Where it is running

• University of Maryland — Baltimore, Maryland, United States
• Lahey Hospital and Medical Centre — Burlington, Massachusetts, United States
• Tufts Medical Centre — Washington, Massachusetts, United States
• Ohio State University Medical Centre — Columbus, Ohio, United States
• Cliniques Universitaires Saint-Luc — Brussels, Belgium
• Cliniques Universitaires Saint-Luc — Woluwe-Saint-Lambert, Belgium
• South Health Campus — Calgary, Alberta, Canada
• University of Alberta Hospital — Edmonton, Alberta, Canada
• Vancouver General Hospital — Vancouver, British Columbia, Canada
• Concordia Hip and Knee Institute — Winnipeg, Manitoba, Canada
• QEII Health Sciences — Halifax, Nova Scotia, Canada
• Royal Victoria Hospital — Barrie, Ontario, Canada
• Etobicoke General Hospital — Etobicoke, Ontario, Canada
• St. Joseph's Hospital Hamilton — Hamilton, Ontario, Canada
• Hamilton Health Sciences - Juravinski Hospital — Hamilton, Ontario, Canada
• Kingston General Hospital — Kingston, Ontario, Canada
• Grand River Hospital — Kitchener, Ontario, Canada
• Victoria Hospital, London Health Sciences — London, Ontario, Canada
• Markham Stouffville Hospital — Markham, Ontario, Canada
• Ottawa General Hospital — Ottawa, Ontario, Canada
• Thunder Bay Regional Health Sciences Centre — Thunder Bay, Ontario, Canada
• Humber River Hospital — Toronto, Ontario, Canada
• St. Michael's Hospital — Toronto, Ontario, Canada
• Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
• Regional Medical Center of San Jose — San Jose, California, United States

Full record on ClinicalTrials.gov

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