CliniMACS® CD34+ Reagent System for Expanded Access Use

NO_LONGER_AVAILABLE

Conditions studied: Graft-Versus-Host Disease(GVHD), Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells, Graft Failure, Delayed Graft Function

In brief

CliniMACs is an investigational device used to select and enrich stem cells. The device will select the stem cells with CD34+ protein. The participant will be infused with the CD34+ selected cells in the hopes that it will help the participant engraft. Engraftment is when transplanted stem cells resume production of healthy blood cells.

Key facts

Study ID

NCT02026934

Run by

Joseph Antin

Starts

2013-03-01

Last updated by the study team

2016-11-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged >18 years
• Diagnosis is graft exhaustion.
• Ability to understand and willingness to sign a written informed consent document
• Matched related or unrelated donor must consent to provide an allograft.

You may not qualify if…

• Symptomatic or uncontrolled cardiac failure or coronary artery disease.
• Karnofsky performance status < 60%.

Where it is running

• Dana Farber Cancer Institute — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.