Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program

Completed · Not applicable

Conditions studied: Lung Diseases, Medication Compliance

In brief

The purpose of this study is to understand why patients in the World Trade Center program have continuing breathing problems. This study will improve investigators understanding of breathing problems among individuals with World Trade Center exposure by allowing them to review and monitor medication use, lung function, and examine other conditions that can contribute to problems with breathing. The findings from the study will help investigators understand why some people have persistent lower respiratory symptoms (breathing problems) after their exposure to World Trade Center dust and fumes, and may help guide better management and treatment of these symptoms.

Key facts

Study ID

NCT02024204

Run by

NYU Langone Health

People needed

60

Starts

2014-04-09

Expected to finish

2017-05-17

Last updated by the study team

2021-02-02

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years and <75
• Meet criteria for World Trade Center Environmental Health Center enrollment
• Onset of lower respiratory symptoms after 9/11/01
• Persistent lower respiratory symptoms (> 2 times per week)
• Pre-bronchodilator forced expiratory volume in one second (FEV1) within normal limits
• < 5 pack-year tobacco history
• Not current smoker
• Asthma Control Test Score ≤ 19
• Normal chest x-ray

You may not qualify if…

• Age < 18 years and ≥75
• Lower respiratory symptoms or asthma history pre 9/11/01
• No persistent lower respiratory symptoms
• pre-bronchodilator FEV1 within normal limits
• > 5 pack year tobacco
• Current smoker
• Abnormal Chest X-Ray or parenchymal changes on high resolution computed tomography
• Uncontrolled major chronic illness (diabetes mellitus, congestive heart failure, cancer)
• History of significant non-World Trade Center occupational or environmental exposure
• Allergy to study drug
• Pregnancy, lactation or plans to become pregnant
• Chronic oral corticosteroid use
• High risk of fatal or near-fatal asthma within the previous 2 years
• Other lung disease (Idiopathic pulmonary fibrosis,sarcoid, etc.)

Where it is running

• New York University School of Medicine — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.