Genetic Polymorphisms & The Risk for Sepsis After Trauma

Completed

Conditions studied: Trauma

In brief

The specific aim of this is to establish a cohort of severely injured patients admitted to our trauma center. Investigators will collect DNA, utilizing discarded blood samples, from 3000 injury victims in an effort to identify perhaps 50 - 100 single-nucleotide polymorphisms (SNP) (out of 1000s) that can be used, when taken together, to identify patients at highest risk for developing complicated sepsis and death.

Key facts

Study ID

NCT02021552

Run by

University of Washington

People needed

357

Starts

2013-06-01

Expected to finish

2015-12-01

Last updated by the study team

2016-12-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Admitted to the Intensive Care Unit (ICU) at Harborview Medical Center after suffering a traumatic injury
• ability to obtain a 5 ml blood sample
• Expected to be in the ICU for more than 24 hours

You may not qualify if…

• We will exclude subjects with chronic medical conditions for the reasons stated above as well as vulnerable populations (children, pregnant females, and prisoners)

Where it is running

• Harborview Medical Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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